THE USE OF PROPENSITY SCORE MATCHING TO EVALUATE THE ENDOMETRIAL RECEPTIVITY ANALYSIS (ERA) IN EUPLOID FROZEN EMBRYO TRANSFER CYCLES

To utilize propensity score matching (PSM), thereby creating similar cohorts, to evaluate the impact of ERA using embryos deemed euploid by pre-implantation genetic testing for aneuploidy (PGT-A). Retrospective cohort study autologous FET cycles between January 1st, 2014 and June 30th, 2019 at a single, university-affiliated infertility practice. Patients were included if they had transfer blastocyst in cycle. assigned group an followed least one based on recommendations ERA. PSM was performed total 15 variables that may outcome, including age oocyte retrieval, number prior fresh transfers frozen transfers. A 2:1 control case match attempted analyzed. The primary outcome live birth rate (LBR) per transfer. 110 patients who undergone following 2,550 controls (non-ERA transfers) available analysis. Following PSM, 99 successfully matched 176 controls. There no statistical difference characteristics (non-ERA) any studied, appropriate comparison groups. Selected results from groups before after is shown Table 1. After matching, average embryo 0.32 0.28 non-ERA group. significantly different however PSM. significant group, 51.52%, 56.82% (OR 0.8075; 95% CI, .4931 – 1.3223).Table 1Patient Characteristics Propensity Score Matching (PSM)Before PSMAfter PSMERA (n=110)Non-ERA (n=2,550)PERA (n=99)Non-ERA (n=176)PAge Retrieval, Mean (SD)36.89 (3.63)36.08 (3.72)0.02536.92 (3.64)36.79 (3.81)0.787Prior Fresh ET, (SD)0.30 (0.67)0.29 (0.75)0.9310.32 (0.70)0.28 (0.63)0.635Prior Frozen (SD)1.54 (1.34)0.53 (0.96)<.0011.37 (1.13)1.25 (1.14)0.386 Open table new tab In this underwent FET, there rates versus those did not. Further studies are necessary understand best patient routine adoption